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ChemInform Abstract: The Synthesis and Anti-MRSA Activity of Amidinium-Substituted 2-Dibenzofuranylcarbapenems.

✍ Scribed by Joanne B. Laub; Mark L. Greenlee; Frank DiNinno; Joann L. Huber; Jon G. Sundelof

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
31
Category
Article
ISSN
0931-7597

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Synthesis and Structure-Activity Relationship of C-3 Benzoyloxymethyl Cephalosporins Exhibiting anti-MRSA Activities. -The title compounds, e.g. (VIa)-(VIc), show excellent in vitro activity against methicillin resistant Staphylococcus aureus besides a good stability in human plasma (some yields not