ChemInform Abstract: Synthesis and Structure-Activity Relationship of C-3 Benzoyloxymethyl Cephalosporins Exhibiting anti-MRSA Activities.

✍ Scribed by O. K. KIM; Y. UEDA; M. M. MANSURI; J. W. RUSSELL; V. W. BIDWELL

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 31 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199749266

✦ Synopsis

Synthesis and Structure-Activity Relationship of C-3 Benzoyloxymethyl Cephalosporins Exhibiting anti-MRSA Activities. -The title compounds, e.g. (VIa)-(VIc), show excellent in vitro activity against methicillin resistant Staphylococcus aureus besides a good stability in human plasma (some yields not given). -(KIM, O. K.;