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ChemInform Abstract: Synthesis and Structure—Activity Relationships of Quaternary Ammonium Cephalosporins with 3-Pyrazolylpyridinium Derivatives.

✍ Scribed by Kwan Young Chang; Sung Hoon Kim; Ghilsoo Nam; Jae Hong Seo; Joong Hyup Kim; Deok-Chan Ha


Publisher
John Wiley and Sons
Year
2000
Weight
31 KB
Volume
31
Category
Article
ISSN
0931-7597

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Synthesis and Structure-Activity Relationship of C-3 Benzoyloxymethyl Cephalosporins Exhibiting anti-MRSA Activities. -The title compounds, e.g. (VIa)-(VIc), show excellent in vitro activity against methicillin resistant Staphylococcus aureus besides a good stability in human plasma (some yields not