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ChemInform Abstract: The Newly Synthesized Pyridobenzoxacinone Inhibits HIV-1 Reverse Transcriptase Activity.

โœ Scribed by D. NOWAK; R. GLINKA; T. PIETRAS; M. CIESLINSKI; P. MAZERANT; P. IDOWSKI; M. LEDER; M. SIDORKIEWICZ


Book ID
101870946
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Pyrimidine Thioethe
โœ R. A. NUGENT; ET AL. ET AL. ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 2 views

The effects of substituent modification on HIV-1 reverse transcriptase (RT) inhibitory activities of a series of pyrimidine derivatives, e.g. (I)-(IV), are studied. In comparison with reference compound delavirdine (DLV), compounds (Ia), (II), and (IIIa)-(IIIc) show the most potent in vitro inhibito