ChemInform Abstract: Quinoxapeptins: Novel Chromodepsipeptide Inhibitors of HIV-1 and HIV-2 Reverse Transcriptase. Part 1. The Producing Organism and Biological Activity.
β Scribed by R. B. LINGHAM; A. H. M. HSU; J. A. O'BRIEN; J. M. SIGMUND; M. SANCHEZ; M. M. GAGLIARDI; B. K. HEIMBUCH; O. GENILLOUD; I. MARTIN; M. T. DIEZ; C. F. HIRSCH; D. L. ZINK; J. M. LIESCH; G. E. KOCH; S. E. GARTNER; G. M. GARRITY; N. N. TSOU; G. M. SALITURO
- Book ID
- 112036706
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
The effects of substituent modification on HIV-1 reverse transcriptase (RT) inhibitory activities of a series of pyrimidine derivatives, e.g. (I)-(IV), are studied. In comparison with reference compound delavirdine (DLV), compounds (Ia), (II), and (IIIa)-(IIIc) show the most potent in vitro inhibito