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ChemInform Abstract: The Concept of Docking and Protecting Groups in Biohydroxylation.

✍ Scribed by Anna de Raadt; Herfried Griengl; Hansjoerg Weber


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
33
Category
Article
ISSN
0931-7597

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The aim of this work was to explore the scope and limitations of chiral docking/protecting groups as chiral auxiliaries in the biohydroxylation of unactivated methylene groups. As a model compound, cyclopentanone 1 was reacted with a range of enantiomerically pure amino alcohols 2a-n as well as 7a a