## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
ChemInform Abstract: Thalidomide Analogues and PDE4 Inhibition.
β Scribed by G. W. MULLER; M. G. SHIRE; L. M. WONG; L. G. CORRAL; R. T. PATTERSON; Y. CHEN; D. I. STIRLING
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Stereospecificity of Myofibrillar Calcium Sensitivity and PDE Inhibition in Cardiotonic Thiadiazinones. -Enantiomers of the title compounds (V)-(VII) are prepared by stereoselective synthesis, cf. (R)-(+)-(V), or by standard resolution procedures using (-)-menthyl chloroformate or a chiral hydrazin
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
2-Substituted-4-methoxybenzimidazole-Based PDE4 Inhibitors. -The synthesis of a new family of phosphodiesterase PDE4 inhibitors based on a benzimidazole framework [cf. (VI), (X)] is described. Several of these compounds are orally bioavailable and show efficacy in in vivo models of inflammatory dis