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ChemInform Abstract: Synthetic Study of Marine Macrolide Swinholide A. Stereocontrolled Synthesis of the C11-C23 Segment.

โœ Scribed by T. NAKATA; T. KOMATSU; K. NAGASAWA

Book ID
112023196
Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
26
Category
Article
ISSN
0931-7597

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Synthetic studies on reidispongiolide A,
Synthetic studies on reidispongiolide A, an actin-depolymerizing marine macrolide: synthesis of C11โ€“C22 and C23โ€“C35 segments
โœ Satoshi Akiyama; Eisuke Toriihara; Kazushi Suzuki; Toshiaki Teruya; Kiyotake Sue ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 265 KB

The C11-C22 and C23-C35 segments 2 and 3 of reidispongiolide A (1), an actin-depolymerizing marine macrolide, were synthesized enantioselectively in 12 steps from (R)-glycidyl trityl ether and in 12 steps from chiral ketone 15, respectively.