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ChemInform Abstract: Synthetic Studies on Bryostatins, Potent Antineoplastic Agents: Synthesis of the C17-C27 Fragment of C20 Deoxybryostatins.

โœ Scribed by K. OHMORI; T. SUZUKI; S. NISHIYAMA; S. YAMAMURA


Book ID
112025510
Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
27
Category
Article
ISSN
0931-7597

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Synthesis of the C(17)โ€“C(27) fragment of
โœ Pedro Almendros; Alastair Rae; Eric J. Thomas ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 78 KB

A synthesis of the C(17)-C( 27) fragment of the 20-deoxybryostatins is described in which the key step is a palladium(0) catalysed coupling of a tributyltin enolate with a vinylic bromide.