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ChemInform Abstract: Synthesis of α-(Heteroarylthio)-α,α-difluoroacetophenone Derivatives via the SRN1 Methodology.

✍ Scribed by Conrad Burkholder; William R. Dolbier Jr.; Maurice Medebielle; Samia Ait-Mohand


Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: New General Synthes
✍ Filip Colpaert; Sven Mangelinckx; Maria Teresa Rocchetti; Norbert De Kimpe 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 52 KB

## Abstract The α‐methoxyketones are prepared via deprotonation of the starting propylidene amine (I) with LDA, followed by reaction with alkyl halides and hydrolysis of the imino functionality.