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ChemInform Abstract: Synthesis of Vancomycin from the Aglycon.

โœ Scribed by Christopher Thompson; Min Ge; Daniel Kahne

Publisher
John Wiley and Sons
Year
2010
Weight
22 KB
Volume
30
Category
Article
ISSN
0931-7597

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๐Ÿ“œ SIMILAR VOLUMES

ChemInform Abstract: Total Synthesis of
ChemInform Abstract: Total Synthesis of Vancomycin Aglycon. Part 3. Final Stages.
โœ K. C. NICOLAOU; M. TAKAYANAGI; N. F. JAIN; S. NATARAJAN; A. E. KOUMBIS; T. BANDO ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 27 KB ๐Ÿ‘ 2 views

Total Synthesis of Vancomycin Aglycon. Part 3. Final Stages. -The conversion of the skeletal framework (preceding paper) to the vancomycin aglycon is started by the substitution of the triazene moiety with a hydroxyl group. The triazene moiety is successfully reduced to an amino group by Raney nick

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ChemInform Abstract: Total Syntheses of Vancomycin and Eremomycin Aglycons.
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Total Syntheses of Vancomycin and Eremomycin Aglycons. -Vancomycin aglycon (Ia) is obtained in 40 steps (longest linear sequence) from 3,5-dimethoxybenzyl alcohol (via amino acid 7). Eremomycin aglycon (Ib) is also successfully synthesized through an identical strategy. These syntheses provide dias