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ChemInform Abstract: Synthesis of the C-13 Side-Chain of Taxol

✍ Scribed by Jagat C. Borah; Joshodeep Boruwa; Nabin C. Barua


Publisher
John Wiley and Sons
Year
2008
Weight
11 KB
Volume
39
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Taxol Semisynthesis
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

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Practical Synthesis of Taxol Side Chain. -A practical large-scale synthesis of the taxol side chain is achieved via the coupling of the chiral imine (V) with ketene acetal (II) followed by sequential reactions of lactamization, demethylation, methanolysis, and N-benzoylation. -(HA, H.-

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First and Stereoflexible Synthesis of Vinylogous Taxol Side Chains. -Starting from readily available chiral starting materials (II) and (VI), stereodefined preparations of the taxol side chains (V) and (IX) are detailed. -(YADAV,