ChemInform Abstract: Practical Synthesis
โ
H.-J. HA; G.-S. PARK; Y.-G. AHN; G. S. LEE
๐
Article
๐
2010
๐
John Wiley and Sons
โ 31 KB
๐ 2 views
Practical Synthesis of Taxol Side Chain. -A practical large-scale synthesis of the taxol side chain is achieved via the coupling of the chiral imine (V) with ketene acetal (II) followed by sequential reactions of lactamization, demethylation, methanolysis, and N-benzoylation. -(HA, H.-