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ChemInform Abstract: Synthesis of Spiroazabicycloalkane Amino Acid Scaffolds as Reverse-Turn Inducer Dipeptide Mimics.

โœ Scribed by Leonardo Manzoni; Matteo Colombo; Emanuela May; Carlo Scolastico


Publisher
John Wiley and Sons
Year
2001
Weight
34 KB
Volume
32
Category
Article
ISSN
0931-7597

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๐Ÿ“œ SIMILAR VOLUMES


Conformational Analysis of Azabicycloalk
โœ Laura Belvisi; Anna Bernardi; Leonardo Manzoni; Donatella Potenza; Carlo Scolast ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 312 KB

In an effort to design structural mimics of protein and peptide reverse-turns, the conformations of 5,5-, 6,5-, and 7,5-fused 1-aza-2-oxobicycloalkane amino acids have been evaluated. The conformational preferences of these proline-derived bicyclic lactams have been studied by Monte Carlo molecular