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ChemInform Abstract: Synthesis of Pyrophosphonic Acid Analogues of Farnesyl Pyrophosphate ( I)-(III).

✍ Scribed by A. R. P. M. VALENTIJN; O. VAN DEN BERG; G. A. VAN DER MAREL; L. H. COHEN; J. H. VAN BOOM

Book ID
112023137
Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
26
Category
Article
ISSN
0931-7597

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## Abstract The synthesis of new bioisosteric analogues of farnesyl pyrophosphate where a vinyl pyrophosphonate replaced the pyrophosphate moiety is described. These compounds have been prepared using a Horner–Wadsworth–Emmons procedure and a modified Michelson reaction. They have been evaluated fo