ChemInform Abstract: Synthesis of Pyrazinone Ring-Containing Opioid Mimetics and Examination of Their Opioid Receptor-Binding Activity.
β Scribed by Yoshio Okada; Atsuko Fukumizu; Motohiro Takahashi; Toshio Yokoi; Yuko Tsuda; Sharon D. Bryant; Lawrence H. Lazarus
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 26 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Syntheses of Novel Pyrazolomorphinans and Their Binding to Β΅and Ο-Opioid-receptors. -A number of novel pyrazolomorphinans [cf. (V)/(VI)] are synthesized by reaction of the enolic morphinan diketones (III) with hydrazines and evaluated for their affinity at Β΅ and Ο-opioid receptors in radioligand bi