ChemInform Abstract: Synthesis of Peptides by Solution Methods
โ Scribed by Yoshio Okada
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 23 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
Synthesis of Peptides Mediated by AgCN. -The synthesis of several dipeptides [cf. (V)] and higher peptides [cf. (VIII)] by acylation reactions of amino acid esters with Fmoc-protected amino acid chlorides in the presence of AgCN is described. The coupling reactions are fast, racemization free and ne
## Synthesis of Cyclic Dinucleotides by a H-Phosphonate Method in Solution. -The synthesis of a variety of cyclic dinucleotides (cf. (V); 10 examples) by a solution-phase H-phosphonate method is reported. The products are characterized by spectroscopic methods and enzymatic degradation experiment