ChemInform Abstract: Synthesis of Cyclic Dinucleotides by a H-Phosphonate Method in Solution.

✍ Scribed by F. ZENG; R. A. JONES

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 29 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199738260

✦ Synopsis

Synthesis of Cyclic Dinucleotides by a H-Phosphonate Method in

Solution.

-The synthesis of a variety of cyclic dinucleotides (cf. (V); 10 examples) by a solution-phase H-phosphonate method is reported. The products are characterized by spectroscopic methods and enzymatic degradation experiments with nuclease P1 and spleen phosphodiesterase. -(ZENG, F.;