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ChemInform Abstract: Synthesis of Peptides Mediated by AgCN.

✍ Scribed by V. V. Suresh Babu; K. Gayathri

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

Synthesis of Peptides Mediated by AgCN. -The synthesis of several dipeptides [cf. (V)] and higher peptides [cf. (VIII)] by acylation reactions of amino acid esters with Fmoc-protected amino acid chlorides in the presence of AgCN is described. The coupling reactions are fast, racemization free and necessitate no addition of base. -(BABU, V. V. SURESH; GAYATHRI,

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