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ChemInform Abstract: Synthesis of P-Chiral, Phosphorothioic Acid Analogues of N- Phospholeucinamide.

✍ Scribed by C. M. THOMPSON; J. LIN


Book ID
101844819
Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
28
Category
Article
ISSN
0931-7597

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## A diastereomeric mixture of R e-and S e-N-[O-methyl phosphorothioic acid]leucinamides were synthesized by thiophosphorylation of leucinamide followed by monodealkylation of the phosphate methyl ester. Individual diastereomers were prepared by a scquence utilizing selective protection of the thi

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