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ChemInform Abstract: Synthesis of C-4-Disubstituted Analogues of N-Acetylneuraminic Acid.

โœ Scribed by D. R. GROVES; M. VON ITZSTEIN

Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Chemoenzymatic Synt
ChemInform Abstract: Chemoenzymatic Synthesis of an N-Acetylneuraminic Acid Analogue Having a Carbamoylmethyl Group at C-4 as an Inhibitor of Sialidase from Influenza Virus.
โœ Kiyoshi Ikeda; Fuyuki Kimura; Kimihiko Sano; Yasuo Suzuki; Kazuo Achiwa ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 38 KB ๐Ÿ‘ 2 views

Chemoenzymatic Synthesis of an N-Acetylneuraminic Acid Analogue Having a Carbamoylmethyl Group at C-4 as an Inhibitor of Sialidase from Influenza Virus. -The synthetic strategy for the preparation of the title analogue (XVI) requires the key intermediate (XII) which is synthesized by the Neu5Ac aldo