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ChemInform Abstract: Synthesis of Novel Hydroxymethyl Substituted Analogues Related to Carbovir and Neplanocin A.

✍ Scribed by Henrik Franzyk; Soeren Rosendal Jensen; Carl Erik Olsen; Jon Holbech Rasmussen


Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
33
Category
Article
ISSN
0931-7597

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A New Synthesis of Carmethizole and Related Nitrogen Analogues. -Short and efficient routes for the synthesis of carmethizole (V), a novel bis-carbamate alkylating agent, and the related nitrogen analogue (VII) are described. Key step is the selective derivatization of the 4,5-disubstituted imidazo