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ChemInform Abstract: Nucleosides and Nucleotides. Part 149. New Neplanocin Analogues. Part 7. Synthesis and Antiviral Activity of 2-Halo Derivatives of Neplanocin A.

✍ Scribed by T. OBARA; S. SHUTO; Y. SAITO; R. SNOECK; G. ANDREI; J. BALZARINI; E. DE CLERCQ; A. MATSUDA


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Nucleosides and Nuc
✍ A. MATSUDA; ET AL. ET AL. πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 36 KB

Nucleosides and Nucleotides. Part 154. New Neplanocin Analogues. Part 8. Synthesis and Biological Activity of 6'-C-Ethyl, -Ethenyl, and -Ethynyl Derivatives of Neplanocin A. -Reaction of the aldehyde (I) with ethynylmagnesium bromide gives the corresponding 6'-ethynyl derivative as a diastereomeric