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ChemInform Abstract: Nucleosides and Nucleotides. Part 167. New Neplanocin Analogues. Part 10. The Conversion of Adenosine to Neplanocin A, a Carbocyclic Nucleoside Antibiotic with Potent Antiviral Activity.

✍ Scribed by S. NIIZUMA; S. SHUTO; A. MATSUDA

Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Nucleosides and Nuc
ChemInform Abstract: Nucleosides and Nucleotides. Part 154. New Neplanocin Analogues. Part 8. Synthesis and Biological Activity of 6β€²-C-Ethyl, -Ethenyl, and - Ethynyl Derivatives of Neplanocin A.
✍ A. MATSUDA; ET AL. ET AL. πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 36 KB πŸ‘ 1 views

Nucleosides and Nucleotides. Part 154. New Neplanocin Analogues. Part 8. Synthesis and Biological Activity of 6'-C-Ethyl, -Ethenyl, and -Ethynyl Derivatives of Neplanocin A. -Reaction of the aldehyde (I) with ethynylmagnesium bromide gives the corresponding 6'-ethynyl derivative as a diastereomeric