ChemInform Abstract: A New Synthesis of Carmethizole and Related Nitrogen Analogues.

✍ Scribed by M. P. HAY; W. A. DENNY

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 30 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199808105

✦ Synopsis

A New Synthesis of Carmethizole and Related Nitrogen Analogues.

-Short and efficient routes for the synthesis of carmethizole (V), a novel bis-carbamate alkylating agent, and the related nitrogen analogue (VII) are described. Key step is the selective derivatization of the 4,5-disubstituted imidazole intermediate (II). -(HAY, M.