The design, synthesis and in vitro biological evaluation of isothiochroman 2,2-dioxide and 1,2-benzooxathiin 2,2-dioxide analogues of coumarin inhibitors of gyrase B are described. Compared to coumarin derivatives, compounds of the 1,2-benzooxathiin 2,2-dioxide series display improved inhibitory pot
ChemInform Abstract: Synthesis of Isothiochroman 2,2-Dioxide and 1,2-Benzooxathiin 2,2-Dioxide Gyrase B Inhibitors.
โ Scribed by Christophe Peixoto; Patrick Laurin; Michel Klich; Claudine Dupuis-Hamelin; Pascale Mauvais; Patrice Lassaigne; Alain Bonnefoy; Branislav Musicki
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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