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ChemInform Abstract: Synthesis of Immunocomponents for the Measurement of Lead (Pb) by Fluorescence Polarization Immunoassay.

✍ Scribed by M. ADAMCZYK; J. R. FISHPAUGH; K. J. HEUSER; J. M. RAMP; R. E. REDDY; M. WONG

Publisher: John Wiley and Sons
Year: 2010
Weight: 30 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199826147

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✦ Synopsis

Synthesis of Immunocomponents for the Measurement of Lead (Pb) by Fluorescence Polarization Immunoassay.

-The development of an immunoassay for lead, based on the inhibition of 5-aminolevulinic acid dehydratase and its indication by fluorescence polarization (FPIA), is described. Five fluorescent tracers (I) and (II) and 3 immunogens (bearing bovine serum albumin chains instead of fluorescein) are synthesized. Lead calibration curves are generated.

-(ADAMCZYK, M.; FISHPAUGH,

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