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ChemInform Abstract: Synthesis of Enantiomerically Pure Amino Acids Containing 2,5-Disubstituted THF Rings in the Molecular Backbone.

โœ Scribed by Anna Schrey; Frank Osterkamp; Alrun Straudi; Corry Rickert; Holger Wagner; Ulrich Koert; Bernhard Herrschaft; Klaus Harms


Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
31
Category
Article
ISSN
0931-7597

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Regioselective Nucleophilic Ring Opening Reactions of 2,2-Disubstituted Aziridines -The Asymmetric Synthesis of ฮฑ,ฮฑ-Disubstituted Amino Acids. -It is shown that, under appropriate conditions, 2,2disubstituted aziridines like (I) and (V) undergo regioselective ring opening reactions at C-3 with carb