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ChemInform Abstract: Synthesis of a Chiral Di(hydroxyalkyl) Substituted Bicyclic Guanidine.

✍ Scribed by I. MUENSTER; U. ROLLE; A. MADDER; P. J. DE CLERCQ

Book ID
112029611
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
27
Category
Article
ISSN
0931-7597

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✍ A. MADDER; I. MUENSTER; U. ROLLE; P. J. DE CLERCQ πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 38 KB πŸ‘ 1 views

The Synthesis of Di(hydroxyalkyl) Substituted Bicyclic Guanidines. -The enantiomerically pure guanidine (XIII) is synthesized by a route based on a methodology developed by Schmidtchen for bicyclic guanidines containing two differently protected hydroxyalkyl side chains. The desired intermediate (X