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ChemInform Abstract: Synthesis of 5-Substituted Quinazolinone Derivatives and Their Inhibitory Activity in vitro.

✍ Scribed by Du-Jong Baek; Yang-Kee Park; Hong Il Heo; Myounghee Lee; Zungyoon Yang; Myounghee Choi

Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

Synthesis of 5-Substituted Quinazolinone Derivatives and Their Inhibitory Activity in vitro.

-Quinazolinone derivatives (IV) and their methyl esters (III) are synthesized and evaluated as nonclassical lipophilic inhibitors of thymidylate synthase (no yields are given).

-(BAEK, DU-

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