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ChemInform Abstract: Synthesis of 2-Amino-2′-diphenylphosphino-1,1′-binaphthyl (MAP) and Its Accelerating Effect on the Pd(0)-Catalyzed N-Arylation.

✍ Scribed by Stepan Vyskocil; Martin Smrcina; Pavel Kocovsky

Publisher: John Wiley and Sons
Year: 2010
Weight: 29 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199909111

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✦ Synopsis

Synthesis of 2-Amino-2'-diphenylphosphino-1,1'-binaphthyl (MAP) and Its Accelerating Effect on the Pd(0)-Catalyzed N-Arylation.

-The title compound (R)-(I), available from (R)-(II) in four steps, is found to exhibit an accelerating effect on the Pd-catalyzed Hartwig-Buchwald N-phenylation of racemic (II) and related compounds. However, no kinetic resolution is observed.

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