ChemInform Abstract: Direct Palladium-Catalyzed Phosphinylation of Aryl Triflates with Secondary Phosphines. Its Scope and Limitations: The Synthesis of Optically Active Carboxylated 2-(Diphenylphosphino)-1,1′-binaphthalenes.
✍ Scribed by G. MARTORELL; X. GARCIAS; M. JANURA; J. M. SAA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 38 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Direct Palladium-Catalyzed Phosphinylation of Aryl Triflates with Secondary Phosphines. Its Scope and Limitations: The Synthesis of Optically Active Carboxylated 2-(Diphenylphosphino)-1,1'binaphthalenes.
-Treatment of aryl triflates with secondary phosphines in the presence of PdCl 2 (PPh 3 ) 2 is found to be a convenient method for making C-P bonds. Phosphine oxides are formed instead of expected tertiary phosphines, which are obtained after reduction. Although a number of aryl triflates can be transformed successfully, this method fails for naphthalene derivatives, for which Morgans' phosphinylation procedure using HPO(Ph) 2