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ChemInform Abstract: Synthesis of 1α,25-Dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (Eldecalcitol) and Related Compounds by the Trost Convergent Methodology.

✍ Scribed by Noboru Kubodera; Susumi Hatakeyama

Publisher
John Wiley and Sons
Year
2009
Weight
12 KB
Volume
40
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthetic Studies on Vitamin D Analogues. Part 39. Synthesis of 1-Deoxyeldecalcitol, a Biologically Interesting Analogue of 1α,25-Dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (Eldecalcitol).
✍ Hirotaka Sasaki; Kohei Eto; Keisuke Takahashi; Jun Ishihara; Susumi Hatakeyama; 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

## Abstract The synthesis of 1‐deoxyeldecalcitol (IV) is realized employing Trost′s methodology involving a palladium‐catalyzed coupling between enyne (II) and bromoalkene (III) as key step.