ChemInform Abstract: Synthesis of 1-Hydroxy-Substituted Pyrazolo[3,4-c]- and Pyrazolo[4,3-c]quinolines and -isoquinolines from 4- and 5-Aryl-Substituted 1-Benzyloxypyrazoles.
โ Scribed by Jan Pawlas; Per Vedsoe; Palle Jakobsen; Per Olaf Huusfeldt; Mikael Begtrup
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 36 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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Some pyrazolo[3,4-c~quinoline-4-ones 1-14 and pyrazolo[3.4-c]quinoline-I ,4-diones 15-17 were prepared and biologically evaluated for their binding at the benzodiazepine receptor (BZR) in rat cortical membranes. The moderate binding activity of 1-5,7,9-10, 13 is attributable to the lack of the optio
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