The synthesis, phosphorylation by guanylate kinase, anti HIV-1 and anti-herpesvirus activity of two acyclic dienyl phosphonate derivatives of guanine are described. (E)-9-(5-phosphono-3-methylene-4pentenyl)guanine (4) was identified as an excellent substrate of guanylate kinase and a significant inh
β¦ LIBER β¦
ChemInform Abstract: Synthesis, Enzymatic Phosphorylation and Antiviral Activity of Acyclic Dienyl Phosphonate Derivatives of Guanine.
β Scribed by J.-F. NAVE; P. J. CASARA; D. L. TAYLOR; A. S. TYMS; M. KENNY; S. HALAZY
- Book ID
- 112032185
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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