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ChemInform Abstract: Synthesis and μ-Opioid Receptor Affinity of a New Series of Nitro Substituted 3,8-Diazabicyclo[3.2.1]octane Derivatives.

✍ Scribed by D. Barlocco; G. Cignarella; P. Vianello; S. Villa; G. A. Pinna; P. Fadda; W. Fratta


Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
30
Category
Article
ISSN
0931-7597

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✍ M. BALLABIO; D. BARLOCCO; G. CIGNARELLA; D. COLOMBO; L. TOMA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

Trimethylpiperazines as Monocyclic Analogues of the . mu.-Opioid Agonist 3,8-Diazabicyclo(3.2.1)octanes: Synthesis, Modeling, and Activity. -The trimethylpiperazine derivatives (IV)-(VII) are tested in binding studies for µ-opioid receptors. Their different affinity towards . mu.-opioid receptors i