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ChemInform Abstract: Synthesis and Inhibitory Effect on Platelet Aggregation and Antihypertensive Activity of 1-Hydroxy-2,5-dihydro-1H-imidazole-2-carboxylic Acid 3-Oxides, 1,3-Dihydroxyimidazolidine-2-carboxylic Acids, and 1,4-Dihydroxy-2,3-piperazinediones.

✍ Scribed by Aleksei Ya. Tikhonov; Dmitrii G. Mazhukin; Larisa N. Grigor'eva; Vadim K. Khlestkin; Natal'ya N. Voinova; Boris Ya. Syropyatov; Svetlana S. Shirinkina; Leonid B. Volodarsky

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

Synthesis and Inhibitory Effect on Platelet Aggregation and Antihypertensive Activity of 1-Hydroxy-2,5-dihydro-1H-imidazole-2carboxylic Acid 3-Oxides, 1,3-Dihydroxyimidazolidine-2-carboxylic Acids, and 1,4-Dihydroxy-2,3-piperazinediones.

-Compounds of type (III), (V), and (VII) (no yield given) are tested for their inhibitory effects on platelet aggregation. Compound (IIIa) shows platelet antiaggregation as well as antihypertensive activities. -(TIKHONOV, ALEKSEI YA.; MAZHUKIN,

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