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Synthesis and Antihypertensive Activity of 2-Imino-2,3-dihydro-5H-1,3,4-thiadiazolo[2,3-b]quinazolin-5-ones

✍ Scribed by Kang-Chien Liu; Ming-Kuan Hu


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
280 KB
Volume
320
Category
Article
ISSN
0365-6233

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3, were synthesized by cyclization of 4-propylthio-1,2-phenylenediamine ( 3) with the corresponding dichlorophosphoryl carbamates/thiocarbamates (2a-J) that were obtained by the addition of alcohols/thiols to isocyanatophosphoryl dichloride (1). The structures of the title compounds were confirme