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ChemInform Abstract: Synthesis and in vivo Antimalarial Activity of 12α- Trifluoromethyl-hydroartemisinin.

✍ Scribed by A. ABOUABDELLAH; J.-P. BEGUE; D. BONNET-DELPON; J.-C. GANTIER; TRUONG THI THANH NGA TRUONG THI THANH NGA; TRUONG DINH THAC TRUONG DINH THAC


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Activ
✍ A. F. COWMAN; L. W. DEADY; E. DEHARO; J. DESNEVES; L. TILLEY 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Synthesis and Activity of Some Antimalarial Bisquinolinemethanols. -Ongoing interest in the development of novel antimalarial agents leads to the synthesis of compounds such as (III) and (VIII). Among all compounds the derivative (VIIIb) shows high biological activity, but the toxicity of this subs