ChemInform Abstract: Synthesis and Activity of Some Antimalarial Bisquinolinemethanols.

✍ Scribed by A. F. COWMAN; L. W. DEADY; E. DEHARO; J. DESNEVES; L. TILLEY

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 32 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199819148

✦ Synopsis

Synthesis and Activity of Some Antimalarial Bisquinolinemethanols.

-Ongoing interest in the development of novel antimalarial agents leads to the synthesis of compounds such as (III) and (VIII). Among all compounds the derivative (VIIIb) shows high biological activity, but the toxicity of this substance excludes its further development. -(COWMAN, A. F.; DEADY,