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ChemInform Abstract: Synthesis and Histamine H1-Receptor Antagonist Activity of 4-( Diphenylmethyl)-1-piperazine Derivatives with a Terminal Heteroaryl or Cycloalkyl Amide Fragment.

✍ Scribed by A. ORJALES; J. C. GIL-SANCHEZ; L. ALONSO-CIRES; L. LABEAGA; R. MOSQUERA; A. BERISA; M. UCELAY; A. INNERARITY; R. CORCOSTEGUI

Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199708233

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✦ Synopsis

Synthesis and Histamine H1-Receptor Antagonist Activity of 4-( Diphenylmethyl)-1-piperazine Derivatives with a Terminal Heteroaryl or Cycloalkyl Amide Fragment.

-The title compounds (I) have the highest biological activities and are as potent in vivo as cetirizine.

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