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ChemInform Abstract: A Novel Histamine 2(H2) Receptor Antagonist with Gastroprotective Activity. Part 1. Synthesis and Pharmacological Evaluation of N-Phenoxypropylacetamide Derivatives with Thioether Function.

โœ Scribed by Y. SEKINE; N. HIRAKAWA; N. KASHIWABA; H. MATSUMOTO; T. KUTSUMA; T. YAMAURA; A. SEKINE


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Hista
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Synthesis and Histamine H1-Receptor Antagonist Activity of 4-( Diphenylmethyl)-1-piperazine Derivatives with a Terminal Heteroaryl or Cycloalkyl Amide Fragment. -The title compounds (I) have the highest biological activities and are as potent in vivo as cetirizine.