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ChemInform Abstract: Synthesis and Evaluation of Dithiolethiones as Novel Cyclooxygenase Inhibitors.

โœ Scribed by Shannon D. Zanatta; David T. Manallack; Bevyn Jarrott; Spencer J. Williams


Publisher
John Wiley and Sons
Year
2009
Weight
26 KB
Volume
40
Category
Article
ISSN
0931-7597

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ChemInform Abstract: New Cycloalkylpyraz
โœ M. C. Cardia; L. Corda; A. M. Fadda; A. M. Maccioni; E. Maccioni; A. Plumitallo ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 29 KB

New Cycloalkylpyrazoles as Potential Cyclooxygenase Inhibitors. -A series of new cycloalkylpyrazoles (VI) (15 examples) are synthesized based on the 1,3-dipolar cycloaddition reaction of nitrilimines (I) with enamine (II) in order to screen their capability to inhibit human cyclooxygenase.