β Scribed by G. Seoane; ET AL. ET AL.
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Synthesis and Biological Evaluation of 1,2,5-Oxadiazole N-Oxide Derivatives as Hypoxia-Selective Cytotoxins. -Synthesis and biological evaluation of a series of new 1,2,5-oxadiazole N-oxide derivatives [cf. (IV), (V), (VIII), (X) (30 examples)] with potential cytotoxic effects are described. Compounds (II) and (VI) prove to be very active, although non-selective. -(SEOANE, G.;
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Several new 1,2,5-oxadiazole N-oxide derivatives were synthesized to be tested both as potential selective hypoxic cell cytotoxins and as DNA-binding agents. The compounds prepared included bis(1,2,5-oxadiazole N-oxide) derivatives and oxadiazole rings linked to naphthyl residues. The compounds were
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v