## Abstract An efficient synthesis of the backbone modified glutathione analogue γ‐(L‐γ‐oxaglutamyl)‐L‐cysteinyl‐glycine (7), characterized by the presence of an urethane O‐CO‐NH linkage replacing the γ‐glutamylic CH~2~CO‐NH fragment is described. The new analogue has been fully characterized by ^1
ChemInform Abstract: Synthesis and Activity of the Glutathione Analogue γ-(L-γ- Oxaglutamyl)-L-cysteinyl-glycine.
✍ Scribed by A. CALCAGNI; S. DUPRE; G. LUCENTE; G. LUISI; F. PINNEN; D. ROSSI; A. SPIRITO
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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## Abstract [Cys‐^14^CO]‐glutathione or N‐[N‐L‐γ‐glutamyl‐L‐cysteinyl‐^14^CO] glycine was prepared by chemical synthesis, with the L,L‐natural configuration and a radiochemical yield of 1% based on sodium [^14^C] cyanide. This labelled compound was used to obtain [Cys‐^14^CO] with a yield of 15%. [
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