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ChemInform Abstract: Structure—Activity Relationships of Phenylalkylamines as Agonist Ligands for 5-HT2A Receptors.

✍ Scribed by Antoni R. Blaazer; Pieter Smid; Chris G. Kruse


Publisher
John Wiley and Sons
Year
2008
Weight
15 KB
Volume
39
Category
Article
ISSN
0931-7597

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✍ M. YAMADA; Y. SATO; K. KOBAYASHI; F. KONNO; T. SONEDA; T. WATANABE 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 1 views

Several substituted 2-pyridazinyl benzoxazole derivatives (VII), (VIII) and (IX) are prepared and evaluated for their utility as 5-HT 3 receptor agonists. A detailed structure-activity relationship study is presented. The most promising results are obtained for the derivatives (VIIa), (VIId) and (VI