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ChemInform Abstract: Stereoselective Synthesis of the 6,7,6- and 6,7,7-Ring Systems of Polycyclic Ethers by 6-endo Cyclization and Ring Expansion.

✍ Scribed by Y. MORI; K. YAEGASHI; H. FURUKAWA


Publisher
John Wiley and Sons
Year
2010
Weight
40 KB
Volume
29
Category
Article
ISSN
0931-7597

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Synthesis of exo-and endo-6,7-Epoxytropanes. -The formation and cyclization of N-protected 2,3-epoxy-4-amino-cycloheptanol derivatives provides a practical route to the title compounds. Whereas the epoxidation of cyclooct-2-enol proceeds with high anti-stereoselectivity as demonstrated in the prece