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ChemInform Abstract: Stereoselective Synthesis of Substituted Tetrahydropyran Rings via 6-exo and 6-endo Selenoetherification.

✍ Scribed by Carmela Aprile; Michelangelo Gruttadauria; Paolo Lo Meo; Serena Riela; Renato Noto


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
33
Category
Article
ISSN
0931-7597

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Synthesis of exo-and endo-6,7-Epoxytropanes. -The formation and cyclization of N-protected 2,3-epoxy-4-amino-cycloheptanol derivatives provides a practical route to the title compounds. Whereas the epoxidation of cyclooct-2-enol proceeds with high anti-stereoselectivity as demonstrated in the prece