Spiro-Substituted Piperidines as Neurokinin Receptor Antagonists. Part 3. Synthesis of (±)-N-[2-(3,4-Dichlorophenyl)-4-(spiro-substituted piperidin-1'-yl)butyl]-N-methylbenzamides and Evaluation of NK 1 -NK 2 Dual Antagonistic Activities. -In order to obtain more potent NK 1 -NK 2 dual antagonists a
✦ LIBER ✦
ChemInform Abstract: Spiro-Substituted Piperidines as Neurokinin Receptor Antagonists. Part 2. Syntheses and NK2 Receptor-Antagonistic Activities of N-[2-Aryl-4-(spiro-substituted piperidin-1′-yl)butyl]carboxamides.
✍ Scribed by H. KUBOTA; A. KAKEFUDA; H. NAGAOKA; O. YAMAMOTO; K. IKEDA; M. TAKEUCHI; T. SHIBANUMA; Y. ISOMURA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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