## Abstract Optimum conditions for the solid–liquid phase alkylation of tetraethyl methylenebisphosphonate are dependent on the nature of the alkyl halide. The benzylation with benzyl bromide takes place efficiently in boiling acetonitrile in the presence of potassium carbonate and a phase transfer
✦ LIBER ✦
ChemInform Abstract: Solid—Liquid Two-Phase Alkylation of Tetraethyl Methylenebisphosphonate Under Microwave Irradiation.
✍ Scribed by Istvan Greiner; Alajos Gruen; Krisztina Ludanyi; Gyoergy Keglevich
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 28 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
Optimum conditions for the two‐phase alkylation of tetraethyl methylenebisphosphonate (I) depend on the nature of the alkyl halide.
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## Abstract Optimum conditions for the solid–liquid phase alkylation of methylenebis(diphenylphosphine oxide) (MBDPPO) and ethyl cyanomethylphosphonate (ECMP) were explored studying the role of phase transfer catalysis and microwave (MW) irradiation, as well as the effect of the cation of the alkal